Vagimones are chemicals released by a gland in the body that send out messages that affect the organism's brain, rendering the organism completely useless and unable to stop bitching. Only a little amount of vagimone is required to alter the organism, and make the newly altered organism a complete pain in the ass.
When an average looking man picks up the most beautiful girl at the party, only to get her home and find that her penis is bigger than his.
Joe: Dude, did you see who Bill left with?
Dude: You mean that tranny Jill?
Joe:Jill is a tranny?
Dude: Yes, and Bill is in for a serious case of vagirony.
Observation by a female comedian of a situation that is strange and funny in an unexpected way.
With her keen sense of vagirony, Sarah Silverman was able to tell a story about her nastyyellow discharge that made her endearing to an even larger number of horny men.
Ruler of Lake Titicaca. Rumored to have a bunghole that gets very angry if it does not receive toilet paper. Cornholio the Great is often seen walking around with his shirt over his head and his hands in the air, chanting songs about his power, and his bunghole.
"I am Cornholio! You do not want to face the wrath of my bunghole, for I need TP!"
Butthead: Shut up, Beavis! (uh huh huh huh)
Beavis: Um, okay. (heh heh heh heh).