Top Definition
The ultimate expression of disbelief, disappointment or surprise.
- Lil' Ol' Weezy got shot again? Van Daaaaamn...

- I just lost my jay'O Bee (job). Van DAMN!

- "VAN DAMN" that chick's got a Jake body!

*Term made popular by Snoop Bloggy Blog
by Snoop Bloggy Blog March 03, 2008

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