An expression used to inform someone they are behaving in a hyper or otherwise overactive manner (i.e. as in the metaphor “bouncing off the walls”) and your desire to have them tone it down a bit.
Marie: Upstairs, downstairs, please shut up!

Bobby: I’m sorry. Was I acting hyper again?
by The Captive Spirit September 12, 2010
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When you take a shower but only have time to soap up your armpits and underwear areas.
I was running late for work so I only had time for an upstairs downstairs shower.
by Whitetigr March 25, 2023
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Refers to da ratio of how much your "upstairs" hangovers (i.e., "morning after" headaches, nausea, etc.) affect da flabby "hangover" --- i.e., floppily-drooping beer gut --- dat gradually develops "downstairs". Generally speaking it'll be about equal; in other words, da more alcohol you guzzle, da more of an "overhang" you'll get at your waistline.
Seeing other folks afflicted with an "upstairs vs. downstairs hangover" should be ample motivation to not start drinking yourself!
by QuacksO November 6, 2022
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A way to describe a two-story house with stairs, so it has an upstairs and a downstairs. When you’re used to only living in a single story house, an upstairs means everything!
Did you hear Monica just bought a house? And it has an upstairs-downstairs!
by itsallaboutkey May 24, 2022
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