Used to describe your amazing time or high you're having (or had) while indulging in your upper of choice. Or you could use it to describe how great you think your upper of choice is.
McDonalds coffee is good, but Dunkin' Donuts coffee is tweakerrific! i swear to god they put cocaine and/or meth in it!
Boys who enjoy yaoi (a genre in Japan that contains sexual and/or romantic relations between two men); literally translates to "rotten boy"; corresponding female : fujoshi