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1.
large, or abnormally huge
That Jewish boy's piska is prodigious
by lilpiska January 14, 2007
 
2.
An exclaimation made by Izzy on the English version of Digimon: Digital Monsters.

Means something exciting or intellectually stimulating. Extraordinary or impressive
"You found relief carvings in the ruins? Prodigious!"
by Luckdragon February 25, 2005