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1.
Acronym. Terminal Lack Of Pussy.

A condition that arises in heterosexual males (or, possibly, homosexual females) who have not had sexual intercourse in a long period of time.

Symptoms include irritability, lack of concentration,lowered standards, hairy palms and morning wood.

Pronounced "Tee-lop"
"Man, it's been six months since I got it on. I've got TLOP so bad, your mom's looking good!"
by Nick Folzie October 31, 2005