The act of getting your unassuming partner in the mood and then having a friend come into the room unannounced, bare ass naked, sportin' a raging boner and ready to shag as if it's just no big deal at all.
Daniel- "I've got something for ya baby. How about a little San Fransisco Surprise?"
Totally Hot Chick- "Fuck yes! I want it now Danny!"
Daniel- "All right love. Turn around and let me give it to you."

Daniel's friend, as he walks into the room unannounced, naked and sportin a throbbing hardon - "Oh, hey guys. Mind if I join?"
by DanK 79 February 3, 2010
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injection of cocaine, heroin and LSD in one potent mix. Extremely euphoric and dangerous.
I`d love to shoot up a San Fransisco Bomb tonight! I`d stay away from those S.F. Bombs if I were you.
by Babylon Drifter December 4, 2008
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The act of vomiting in a woman's vaginal cavity and proceeding to have sexual intercourse.
Dude, I hooked up with this chick last night when I was hammered. I started eating her out and I threw up a little. But, bro, I was like 'fuck it' and gave her the San Fransisco Ramlet.
by trilovecurry October 8, 2009
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The vagina of a man who had a sex change to a woman who lives in San Fransisco.
"Dude did you see Karly's San Fransisco Muffin last night? that snatch didnt even look like a pussy"
by PheeNoIVI September 28, 2009
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1. Also known as a San Fran, a person who acts like an asshole for no reason at all

2. Someone who does something extremely irrational
1. Let me inside the club you Sanfransico Cocksucker

2. What do you mean you arent going to drive me to the game? Quit being a San Fransisco Cocksucker.
by MrBrownstone June 22, 2005
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Slang term for a blowjob. San Fransisco has a reputation for being one large gayborhood, hence the term.
"I heard they were both fired when she was caught giving him a San Fransisco handshake in the stairwell."
by CaptainButtercup August 30, 2009
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