A)To take a shit.

B)When you have to poop and you post up on the shitter.
A)Man, I really have to post up, I need to find a bathroom soon.

B)Every morning my boyfriend posts up with his PSP for a good 30 minutes.
by Sarah Lambert March 3, 2008
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Literally means nothing, but generally used as a greeting or goodbye. The phrase may also be used to describe a moment of guys being dudes.
*Kyle walks down hallway*
*Sees friend walking to his direction*
"Hey dude, Posted Up in York!"
"Haha, Posted Up in York!"
*Kyle and friend continue walking to their destination*
by kalechow March 6, 2019
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If a girl is taller than you and in basketball terms could "post you up" and score on you then therefore she is not dateable for you.
John you can't go out with Jennifer she doesn't pass the Post-Up Test. She's 5'11 and you're only 5'9 she could easily back you down worse then Shaq.
by Ballzack05 April 11, 2020
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The prepose for making out after a date.
The date went well, I posted up but he had no follow through.
by Matt taylor April 20, 2005
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When co-workers gravitate to a certain area (usually around a manager's desk or someone they are trying to seek approval from) and talk about boring topics such as kids or shopping.
Damn kid, there goes Karlena and Jessica with post up hour again!
by anklebreaka1 July 25, 2008
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Also known as: Postin' it up, rock-it-hard, blockin' hard, etc.

The act of one or more people assuming random gangster poses, usually poses that originated from Run-DMC in the 80's. Crossed arms, gangster hats, bandannas, and Gumball 3000/Puma's and 13-14 year old girls are a must to correctly "Post it up."
Kenneth, Seth, and Jeff post it up hard.

Jeff tries to get girls to post it up with them. And it never works.
by Jeffrey Giraffe May 3, 2007
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