1. Humanity's greatest creation.
2. Humanity's greatest solution.
We can sel dis nuke for a shiet ton'a dough, howbowdah?
by Iamawesomedog August 22, 2018
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Verb: To destroy through the use of nuclear weapons, or to otherwise destroy figuratively. Prior to 1975, used only as a noun, until coined by me during a game of William's "Defender," at a MD video arcade.
Nuke `em!
by Tron-fur-knee June 1, 2016
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A hook-up that is so intense, it's of nuclear proportions.

Variations: Nuke it out; Nukin'

Caking, smashing, nailing, boning, etc. all have similar meanings, but none can match the intensity level associated with "nuking."
-Bro, did you ever end up gettin' with that bitch last night?
-Dude. We nuked it out for the longest time, it was unbelievable. I'm gonna try and nuke her again later tonight...
-Shit, man...I saw you guys cakin but I didn't think you'd actually nuke her.
by garhcSD January 14, 2011
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When an excessive amount of semen is released during ejaculation.
"Hey man, how was your night last night?"
"It was pretty good, but my favorite part was when i nuked all over your mom's face..."

"Man last night i was wanking off, and i nuked so hard my toilet overflowed!
by BallsMan5 February 12, 2012
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When a fat guy farts a wet fart that makes the room smell horrible. No one lives through it. He is unaware that he does this till people start to die.
Fat guy: why is everyone dead? AHHH CRAP I NUKED THE PLACE!!
by DARK3R February 9, 2009
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