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When you tell someone to just go ahead and just do it, regardless of their objections.
She told me the word was misspelled, but that's how the client wanted it, so I told her to just "Nike it!"
by Another Ad Guy January 09, 2014
refers to nike's slogan just do it. when someone is being a pussy tell them to "nike it" meaning just do it
mike: dude i don't think i can do this...

tyler: come man, dont be a pussy! Nike it man!
by squwirl April 26, 2010