1) An alternate to 'motherfucker' to the impersonal; more accurately directed at inanimate objects and situations, whereas motherfucker is generally reserved for person-to-person communications.
2) A dire situation or circumstance.
3) Short for 'the mother of all bitches'.
A PG way to say motherfucker. It was often used in clean versions of movies where they didn't want to censor it the normalway.
David : * in sync with the TV * Die motherflipper
Wife : * in sync with the TV * Die motherfucker
David : Stop swearing, this is the clean edit version
Wife : Oh shut up you pussy