Top Definition
a very fatal, rare form of cancer. Also is the really annoying commercial.
Did you see the mesothelioma commercial? its on like every minute.
by Rlvers March 11, 2011
1 more definition
Deadly form of lung cancer caused by exposure to asbestos.
That dude has mesothelioma - he's fucked.
by toddieg August 16, 2006

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