Anal penetration, with no warning, no luracation, or condom.

origin; Holyoke Ma.
Don't make me megatron you!
by Clyde Harper February 8, 2009
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Something that is huge or really big, usually used as if something is really bad (because Megatron is the bad guy in Transformers)
Man, I had a megatron exam in math, and I'm sure I bombed it.

That guy is a megatron douche!
by Cerpin Taxxt October 29, 2006
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A crazy ass bitch who will stop at nothing to get fucked up. A good friend, but also a good friend who is always willing to fuck some shit up. The girl who gets high before night class and brings fruit loops. The girl who almost quit lacrosse to go on spring break, because she wanted to fuck shit up so badly.
"Did you tron last night?"
"Oh shit, Megatron was out last night"
by thebabymaker January 24, 2013
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Ultimate fail, misdoing, fatal error, or all around badness.
-I tried to ask her out, but she walked away and hooked up with some random dude.
-what a megatron
by smiley808 September 7, 2010
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Megatron is the street name for the legal high mephedrone, it's sold in many herbal high shops under many different names i.e shake and vac.
Let's do some Megatron
by Frogbox September 4, 2009
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An obese female, usually capable of consuming large amounts of "energon" such as chips, pizza, hamburgers, etc. in a single sitting. Megatrons tend to be rather obnoxious or loud, often being heard over most talk in a room.
"Bro, I was trapped behind this megatron at Wendy's. She was so loud, I couldn't hear anybody else in the room!"
by hurr durr herp derp January 5, 2012
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