When a gurl is really stupid and sense less, not knowing the easy things but is smart when it comes to that hard education in other words lopy.
Damnn that gurl is sooo lupy! Shes really dumb and funny!
by TooDown August 28, 2009
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What House M.D. thinks every patient has before he comes up with the correct diagnosis.
Foreman: I think it's cancer

Chase: No his white cell count isn't high enough

House: You're both wrong it's Lupis

later..........

House: a broken finger.
by spartan kirkus November 19, 2009
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Lupis is a person who only cries and gets bullied by his friends. He is an egg with big ears.
Friend 1: Do you see this person crying?
Friend 2: He must be Lupis
by cizu October 22, 2022
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An wild wolf with horns (it can be any kind and antlers), wings (either dragon or feathered), a feather tail (like a dutch angel dragon), and fur patterns like Native American marks, tiger stripes, or snow leopard sports, etc. Lives in North America,Europe, and Asia (this is made up lol)
The hunters ran away after the Capricornius Lupis roared at them.
by Swaggie The Fox November 25, 2018
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A teacher who is afraid to go on a rollercoaster!
LUPI ROLLERCOASTER won't go to the theme park because she doesn't like rollercoasters
by asdfghjasdfghjasdfvbnm November 8, 2023
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The best friend you could ever wish for

Bestie of pilu

Best duo with pilu
Pilu and lupi are always laughing and having fun
by Emma1737282 January 20, 2022
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A faggot that goes to somers schools. He’s a pussy
“You here what Lupi did?”
“Yeah that kids a faggot that smokes
by Nolan kavangh March 2, 2020
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