Top Definition
etim. Spanish for "crazy", "insane", "mad".
Ese tío está loco
("That guy's crazy")
by Cervantes November 28, 2003

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(adjective) crazy; insane.
Do you think he's lil' loco?
by Fangsta March 17, 2003

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insane, crazy (from spanish)
He went loco when they saw what he did to his car.
by Light Joker February 13, 2006

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Spanish word meaning crazy.
El es un poco loco -> He's abit crazy.
by i♥ue August 08, 2010

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crazy/off the hook/insane
i am oh so loco mama dint raise no chump i dont talk 2 po po!
by MC PAKMAN November 08, 2005

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a fuckin crazy/insane person
yo dawg dont fuck wit Carlos man that niggas hella loco
by InfamousMami December 07, 2004

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Crazy, or insane.
But is often said to mean very fucked up on drugs.
"Is that dude loco, or what man?
"Shit man! I'm fucken Lohhhcohhhhhh right now!"
by Diego July 18, 2003

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