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1)K.O. as in "knocked Out" can be used in life when someone is unconcious and also appears in fight games when there is a victor and the loser is K.O.

2)the dyslexic way of saying OK.
(I have a dyslexic friend and this is her joke, its not meant to be hurtful or nasty in any way)
PersonA: hey PersonB, u want to go to the movies?
PersonB: ko

PersonA: Im going to knock u out
PersonB: ... *is knocked out*
PersonC: K.O.!
Ko by ThatGirl January 13, 2005
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"KO" is the equivalent to the meaning & abbreviation of the letters meaning "OK" and was used on "Mork & Mindy", which is a t.v. series that had aired from 1978 to 1982. Mork is one of the main characters in the series, and an alien from the planet Ork. He would commonly reverse the proper order of human words and phrases that he spoke, by mistake
"Owie! Shazbot, shazbot, SHAZBOT! I stubbed my little toe when I tripped over the footstool Mindy, and it hurt!!! You didn't even ask me if I was KO!!!"

(Mindy replies)
"Oh, Mork! I'm sorry- did it hurt? I think you meant to say that I didn't ask you if you were "OK", on Earth we ask if you are OK if you hurt yourself, not "KO"!!!

***Proper credit must be given to the true comic genius of Robin McLaurin Williams (July 21, 1951 – August 11, 2014) R.I.P.
KO by green eyed lady 13 August 18, 2014
Related Words
Kobe Kool-aid kook kobe bryant kool koala korn Kody koreaboo ko
totally intoxicated
unable to stand / speak
short for "knocked out"
that boy drank too much - he's k.o.
ko by will December 11, 2003
1. a knockout

2. to knock someone out
If he manages to KO him every time he'll be braindead pretty soon.
KO by Light Joker March 29, 2007
n00b: okies, itz gettin l8, im gunna KO ^_^ 99!!!!!11
ko by swishersweets April 9, 2008
A Canadian Musician with most of his songs about smoking weed. Give him a listen.
Hey man did you hear that new KO song about him selling crack when he was younger?
KO by lolidkwtnm July 2, 2011
a seriously sexy female. A tragic muse that you can't help but worship.
ko by Anonymous September 26, 2003