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1.
The single most versatile word in the history of the world. It basically means "done", but it can refer to many diverse situations. "Keeshed" can mean Drunk, Full, High, Tired, Passed Out, Screwed, or any number of other things.
When John and Austin came back from downtown they were so keeshed that they fought in the hall for 45 minutes before passing out on the futon.
by Smitty2112 January 08, 2010
 
2.
feeling the effects of marijuana, or simply put as high or stoned. Also can be used as a word describing how tired or worn out you are after smoking weed.
Digg and Michael were keeshed after rippin a bowl at the park.
by Officer Billy April 18, 2009