ISSF 

Acronym for:
I'm So Sexually Frustrated.

X: "I SWEAR dude, she was grinding against my package nonstop at the party!"

O: "Wow, sounds like a real ISSF moment.."

ISSF by wchistia July 6, 2011

ISSF 

"Insert Sideways Smiley Face"
because emoticon is a stupid name, and lol is usually used to mean "smile." plus, using a cryptic acronym to stand for an over-used geek phenomenon has a beautiful circularity.

"i wanted to get my definition into UrbanDictionary.com, ISSF."

ISSF by meme March 22, 2005