Man 1: Aliright bo.

Man 2: yo holmes, tisra safe.
by JimBob MacGregor June 14, 2003
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Gangster slang. What you would call a good friend, a stranger, or even mockery against an adversary.
Was`sup, holmes.
You got a problem with it, holmes?
by SD December 18, 2003
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Holms is the short term of hommie. Some people incorrectly spell it homs but that makes no sense. The world holms is used when talking to only a kewl person. Mainly used when greating like what up holms!
"Abra Cadabra holms" -Talladega Nights
by Not Danny Glunz September 29, 2006
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"Holmes" (L is not silent) is the correct Ebonics pronunciation which has a history of being used equivalently with, "dude", "guy", "man" or similar non-familiar alternatives not in the third person.

It was made popular in late 60s East Coast slang, and then later devolved into, "homes" (silent L) at which point it was incorrectly assumed to be short for, "homeboy".

"Homeboy" is typically expressed as a familiar, friendly term often in the third person.

Unlike homeboy, holmes can be used in a variety of ways to denote friendship, aggressiveness, or dubious curiousity.
"What you lookin at holmes?"

"Nice score on that one holmes!"

"Hey Holmes..."
by mpoodle January 7, 2012
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A hispanic-slang; the hispanic version of homies usually used after every sentence.
Guy 1: Yo you gotta a problem with me, holmes
Guy 2: No I'm cool, holmes
by Kanye West Biggest Fan! May 31, 2009
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The greatest detective that ever lived (although he never actually lived since he's a fictional character).
Read a book about Sherlock Holmes and everything will be clear to you. And remember, books > movies.
by Sherlock Holmes August 14, 2007
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basically slang for "buddy"
see word "homie"
white boy trying to act gangter: "what is up holmes?"
by gangsta mang March 13, 2005
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