Herpderpes is a sexually transmitted case of stupidity, symptoms of this include general herping and derping, and is not limited to brain farts and mind queffs. Can be extremely contagious during the early onset of the disease, and has no cure.
John, do you have herpderpes, everyone around you seems to be getting stupider
by mackattack3345 February 24, 2011
Get the Herpderpes mug.
Another way of saying duh.
Stacey: I ordered the food, it will be here in 10 minutes.
Louise: okay when will it be here?
Stacey:herpderpderpderpdurrrr.
by TheObieOne May 10, 2010
Get the Herpderp mug.
Herpderp is the smell of herpadermis.
Being able to smell ones face in the case they have herpes of the face.

The process of facial screening before sexual intercourse of the face
"i had to herpderp her face with my tongue to make sure she was clean
by HerbDerby July 26, 2010
Get the HerpDerp mug.