1 definition by mackattack3345

Top Definition
Herpderpes is a sexually transmitted case of stupidity, symptoms of this include general herping and derping, and is not limited to brain farts and mind queffs. Can be extremely contagious during the early onset of the disease, and has no cure.
John, do you have herpderpes, everyone around you seems to be getting stupider
by mackattack3345 February 24, 2011

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