A particularily painful sharp, gastrous pain, caused by a night of heavy alcohol consumption, usually following the morning after consumption occurs.
*flatulant sounds* "Aw man, I have gut rot from the 03 we had last night!"
by Ricebabe January 15, 2004
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A very serious stomach ache that is the result of bad food or prior malt liquor consumption that occurs just before a sloppy case shitting.
Gary: Hey Crid why do you look like someone kicked you in the balls?

Crid: Because, I have Gut Rot from Terry's tacos I ate yesterday.
by Cridis shortstacked December 3, 2007
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When you haven't eaten anything in a long period of time, and your stomach churns and aches because it is empty. Feels like nausea, but nothing to throw up.
Person #1: "Have you eaten anything today?"
Person #2: "No, I've got some serious gut rot going on."
by black bear April 9, 2006
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An extreme feeling of sickness in one's digestive track that almost always results in a very severe and excrutiating case of explosive diarhea.
Eating at Coney Island and Shitney almost always gives me gut-rot.
by Erin August 14, 2003
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When your insides feel like they just barfed on themselves.
"Hey I feel like I have to take a big dump, but I can't, so I must have gut rot."
by Wessie Jittaker July 2, 2007
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A catchall term for heartburn, acid reflux, ulcers, and other things where your stomach feels like it's digesting itself. Since for the most part, you take the same pills for them, there's rarely a need to differentiate in casual conversation.
"Oh man, I've got some killer gut rot, anyone got some Rolaids?" "Here, take a Zantac, it'll work better. And maybe you should stop working 80 hour weeks and eating garbage?"
by roxyhead August 24, 2011
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Hapens after you drink too much beer.
The next morning.
"Ouch, my stomach hurts." said sally
well, explained gary "If you didn't drink all that Colt 45 you wouldn't have gut rot."
by Caroline May 31, 2003
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