Top Definition
GHS or geek in high school syndrome: a male who was considered a geek or a nerd in high school, but has tried to shed that image in adulthood. After high school, he joins a fraternity, pumps a lot of iron, dates bimbos, and drives flashy cars to compensate for not being popular in his youth. Ironically, as nerds, they were sweet and nice, but now have become arrogant and cliche. It is a very sad condition, and there is no known cure at this time.
Ryan used to be so nice in high school, but now he is arrogant and unpleasant to be around. He has a severe case of GHS.
by Snowite July 01, 2010
Short for: Guitar Hero Sluts
"you guys are GHS"

"you are just jealous dailyn"
by MrT1ki May 05, 2007
Grand Hustle Snatch
A girl who is impossible to get with.
Damn that bitch is a GHS
by Eric Acosta January 08, 2008
Abbreviation for Genetic Half Siblings. With identical twins, when they grow up and marry, their children will be genetically from the same person-- the cousins will be half-siblings, genetically. Variations are Genetic Half Sister and Genetic Half Brother
Eric and Derek are identical twins. Eric married Lucy and had Ike; Derek married Susan and had Lisa. Ike and Lisa are GHS's.
by Meg/Ana April 22, 2006

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