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1.
A disease that a person gets when they are extremely unfunny. The disease can simply be cured by making a funny joke but once it happens too much it becomes a very serious life-threatening disease. There are many celebrities with Fox Syndrome such as Rob Schneider, Adam Sandler, Robin Williams, Denis Leary and every MADTV cast member.
Guy 1: I have a very funny joke!
Guy 2: What is it?
Guy 1: Guess what?
Guy 2: What?
Guy 1: Chicken Butt!!!
Guy 2: I think you might have Fox Syndrome.
by 21.33 December 21, 2011
13 2
 
2.
Inability to commit to a new television show until after it's first season has aired.
I can't risk becoming involved with a new show just to have it cancelled after one season. I guess I'm suffering Fox Syndrome.
by elwaz February 11, 2010
6 0