Ay Yi Yi 

An expression used to show frustration, hopelesses, sadness, annoyence and so on and so forth.
Pronounced Eye- Yii- Yii

"Damn, I have so much work. Ay yi yi."
"Fred fell down the stairs AGAIN? Ay yi yi."

Ay Yi Yi by Bowser13 February 14, 2008

Ay yi yi 

When said with an upward inflection: A way for a fellah to succinctly say to a lady walking down the street "Yo, lady, you look smokin' hot today!"

"Ay yi YI"

Ay yi yi by elle-e-elle April 30, 2010