An expression used to show frustration, hopelesses, sadness, annoyence and so on and so forth.
Pronounced Eye- Yii- Yii
"Damn, I have so much work. Ay yi yi."
"Fred fell down the stairs AGAIN? Ay yi yi."
by Bowser13 February 14, 2008
When said with an upward inflection: A way for a fellah to succinctly say to a lady walking down the street "Yo, lady, you look smokin' hot today!"
"Ay yi YI"
by elle_e_elle April 29, 2010

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