Top definition

1. To "Man Up" but with the attitude of an Asshole.

2. To go from nice guy to an Asshole in an instant.

3. To be an Asshole!
Guy 1: If that guy is looking for a fight then I'll just "Asshole Up" and rip his fucking head and shit down his fucking throat!!!

Guy 2: Damn dude, calm the fuck down!
by LenDog 2 September 25, 2009
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