Top Definition
"Asshole-Up"

1. To "Man Up" but with the attitude of an Asshole.

2. To go from nice guy to an Asshole in an instant.

3. To be an Asshole!
Guy 1: If that guy is looking for a fight then I'll just "Asshole Up" and rip his fucking head and shit down his fucking throat!!!

Guy 2: Damn dude, calm the fuck down!
by LenDog 2 September 25, 2009

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