Top Definition
Regional (Syracuse, NY) derogatory term used to describe someone the speaker dislikes. i.e. A jerkoff, a stroke, a moron, etc... Encompasses many insulting terms without actually stating them.
Person one: "Hey, did you hear about what your neighbor did?"

Person two: "Screw him, he's another one."
by Dickie68 August 30, 2012
A very annoying phrase that DJ Khaled says in the beginning of almost every song since January 2014. It used to be "We The Best", now it is "Another One"
Joey: Hey bro you gonna see that girl today?
Haseeb: We're just friends man
DJ Khaled: Another One, Another One.
by arsalansiddiqui November 18, 2015

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