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1.
0_o
An expression of surprise used on Instant Messaging services.
Person One: I got a sex change!
Person Two: 0_o
by Zak September 06, 2003
 
2.
0_o
To textually raise one's eyebrow as an expression of shock, bemusement, plain amazement or in any 'lost for words' scenario.

Similar to a combination of MSN ^o) and :| and :O, a generally mutli-purpose smiley!

Extreme usage on Active Worlds within SW City as the lingo of choice.

Other alias's are: o_0
Person A: OMG OMG OMG I want to marry you!
Person B: o_0
Person A: 0_o
by Mark Randall January 06, 2005
 
3.
0_o
bottled up excitement combined with frustration, sarcasm, asian persuasion, and deprivation. all of which are controlled by the cerebellum.
(after their first night together.)
girl: i think i love you.......
guy: yeh once you pop the fun dont stop!
girl: 0_o
by bankie barnes November 02, 2009