irritable bowel syndrome is a type of person that makes weird sound effects when they are talking and refuses to kiss their boyfriend at the door.
Oh that irritable bowel syndrome she left my man hanging at the door and started squawking while she was telling me about a hike she went on.
by zeebeegeez November 16, 2018
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(n) a rare but serious effect, most noted by journalist Tucker Carlson, wherein Sidney Powell gives you earful in reaction to numerous interview requests.

Interview requests that ask you to talk, on air, about highly consequential, ongoing litigation

Etymology: cf. Sidney Powell; a federal attorney, best known for her defense of Michael Flynn and for having brass balls bigger than most men in Washington DC
Maria Bartiromo from CNBC knows how to get an interview without causing irritable Powell syndrome // she's also rather hot
by Content-ment411 December 22, 2020
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when your pipe runs out of weed and it becomes angry, also known as IBS (irritable bowls syndrome)
my pipe has irritable bowls syndrome and is angry
by SUPAHIGHWAY May 10, 2016
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A syndrome when you drop so much bottom banter it hurts
Crostin: Yo PJ
PJ: Yo you got irritable bottom syndrome (IBS)?
by razvanovicio September 20, 2022
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1: Damn, dude I got a Irritating Stick.
2: You can't just itch your cock in public, man.
by exoskeletal August 18, 2022
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