"no guff" 

means.... "no shit dick tracy... are you a loser not to know that"

one: madonna is a whore
two: yeah... "no guff".

"no guff" by oneleggedracer April 23, 2006

no guff 

A sarcastic phrase used to describe the stupidity of another person's statement. Relatives of the phrase include "No kidding!" and "No shit!"

Glen: "Carlos came into my office and asked if I had a floppy drive. I told him that I didn't."

Andrea: "No guff"

no guff by digi::icon June 22, 2006

no guff 

Kinda like “no shit” or “no kidding.”
Wayne Campbell from Waynes World coined this phrase.

Wayne and Garth walking through a desert.

Garth: “Wow we really are in the desert.”
Wayne: “Sha, no guff.”

no guff by thetartag March 27, 2020

No guff, chet 

1. Interjection used to express disbelief at an understatement. Obviously; no shit.

2. Statement used to express general agreement with a friend. Fuckin' A'; for real; I heard that.

(Chet can be dropped in any usage)

1. Bill: Your leg is on fire!

Tim: No guff, Chet!

2. Carl: We really stepped in it this time.

Joe: No guff.

No guff, chet by squeezmunky February 16, 2010