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Abbreviation for "two weeker", used to describe a person who does something or goes somewhere for two weeks. Sometimes spelled "tw'eeker" or "tw'weeker"
How long are you goin' to sleepaway camp?
I'm gonna be a tweeker
tweeker by Wolfdog September 7, 2007
San Francisco Club Kid who frequents the Internet Adult Store at tweeker.com.
That tweeker bought all of them online at tweeker.com.
tweeker by Gary A April 16, 2004
a person addicted to marijuana.

Orgin: bayarea late 80's

a Pothead.
I never invite that tweeker cuz hes always high and just sits around and not getting involved.
Tweeker by Lec2 March 6, 2003
Tweeker
The tweeker was so tweaked he couldn't even sit still, he looked like he to many places to go.
Tweeker by Discreet October 3, 2021
A meth user! Someone who is all jacked up from drugs is a tweeker!
Hey theres josh ayala the tweeker! What a waste of sperm!
Tweeker by Chelserie hehe October 30, 2021
Is best described as a Sticky fingered , corpse like individual whom demonstrates a compulsive addiction to both sexual acts and lying . Tweekers have also been observed expressing themselves by way of rage , causing many to become uneasy around them .
“ get a load of this TWEEKER , poured the dope out onto his watch face so he can take it home n smoke alone”
Tweeker by GuttersGARAGE March 11, 2022