tweak 

Using your index and middle finger to squeeze someone's nipple; "the power of two becoming one"; can add "power" as a prefix to denote hard or rough; can indicate holidays (e.g., Merry Tweaksmas; Happy Tweaksgiving; St. Patweak's Day)

"It's time for your tweaking--give up those tender nipple buds!"
"We wish you a Merry Tweaksmas and a Happy New Tweak Year!"
"Okay, you can tweak me, but no power tweaks. Got it?"

tweak by Freak Nastay February 25, 2003

Tweak 

A word most often used with the pretext "to pull a", this meaning of the word originated in Arroyo Grande, and refers to a resident who own a .50 cal handgun, and is the definintion of "badass"

Victor: Yo! Come watch me smoke this fool!
Tyler: Hey man! Calm down, you're about to pull a Tweak!

Tweak by k man gg May 7, 2009

Tweak 

Thaaa coolest kid in south park

tweak is cool

Tweak by tweak July 18, 2003

tweak 

a girl thats always wanting to get it in

that freshman be tweakin all ova the place. this is her fourth abortion

tweak by yolandaishurr February 18, 2011

Tweak 

To not relax; to not chill; to mimic someone suffering from a unique combination of schizophrenia and terets, presenting a lack of logical thought upon speaking.

Don't tweak bro, relax.

I'm chill man, I never tweak on acid.

Relax for a second, or you might start to tweak.

Tweak by TweakOrBust December 5, 2017

Tweak 

A meth addict who is stuck doing pointless actions for long periods of time.

After hours of tweak activities, Theodore finally fell asleep.

Tweak by Juice Jonson May 8, 2018

Tweak 

when you have a freak out .

When you go ape shit.

I'm gonna tweak the fuck out!

Bro, that kid fucked with me and i tweaked on him!

Tweak by pegasus12344 December 26, 2018