Especially referring to someone you have a history of hooking up with when drunk, but who you usually reject or refrain from said hookup with when sober.
Origin: When sober, you may or may not want a cheeseburger, but when you're drunk, you can never turn it down.
Friend 1: Did Luke hook up with Lauren last night?
some little cat, old man, granny, your momma, or anyone who walks around with a big ass smile on their face with no obvious reason. they might have "fish eyes" when they are being a 'cheeseburger'. for whatever reason, this 'cheeseburger' is super happy and they ain't nothin' nobody can do about it.
A fucking idiot. Basically making fun of some dumbass crackhead who has no idea your making fun of him or her. You can also use this at the end of every sentence and you'll notice no one ever picks up on it.
Some guettocrackhead asked me for money to get beer, I told him to go fuck himself cheeseburger.