in german, the word sounds like the pronoun "wen". often used to express a lack of interest.
"wayne interessierts?" (who cares?)
by danse May 28, 2004
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Being duped, tricked, hoodwinked into thinking one thing but having the exact opposite actually occur
I waited and waited for the phone call that never came, i guess i was Wayned.

I Wayned that guy out of 20 bucks.

She was Wayned at the altar.
by musqueam May 27, 2009
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It's like when they are too cool for a name or words, so they are called waynes, it's the only sensible name for something soo super cool
"Oh, hes such a waynes alberto soy"
by Mr.Ching June 14, 2009
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A shameless act of increasing ones post count on an internet forum, without actually contributing anything meaningful.
+Wayne "That's great"
+ Wayne "Can't wait to see how that turns out"
+ Wayne "Google says.."
+ Wayne "Good choice"
+ Wayne " I Like that"
by GolfGTI.co.uk November 21, 2011
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To get drunk, To drink a copious amount of alcohol
"Whoa, this guy is gonna past out in a ditch, he must be wayned."
by the_doc October 2, 2006
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the act of getting so fucking high from marijuana you're barely able to function and your voice gets low and raspy such as the permanent state of the well known rapper lil wayne. Originated a the university of alabama.
Oh my god I'm so wayne right now!

I want to get so wayne tonight!

Dude I've got so much weed we're getting wayne off our ass tonight!
by TE squared March 8, 2009
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"wow" or "damn" in dominican/colombian/panamanian slang
-wayneeeee mira esa tipa!

-damn look at that girl! (in english)
by mateoyfranco May 24, 2011
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