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1. A guitar designed so that it may be strummed with the left hand rather than standard guitars, whose body and string arrangement are designed to be strummed with the right hand.

2. Someone who uses their left hand to strum whether they are completely left-handed or not; also someone who is completely left-handed.
1. I own a regular guitar, but it's strung like a lefty so that I can play it.

2. Jimi Hendrix was/is one of the few famous leftys.
lefty by D-Shiznit July 7, 2005
A seriously ugly girl but gives it up to anyone. It is derived from the saying: "lefty loosy, righty tighty" when trying to remember which way to turn bolt to loosen it. Also commmonly said is "if it left it can't be right. If it's not right it must be wrong." Which refers to the expression "she looks wrong"
"Man she was a lefty but I was desperate to get some"
lefty by Jacob Parker April 26, 2005
A girl that you have no interest in as a partner, but you will nonetheless be down to “cuddle.”
1st guy: “ayy man who was that girl you were sitting by at lunch?”
2nd guy: “aw she’s just a lefty. Know what I’m sayin?”
1st guy: “whatever faggot”
Lefty by Extrasaucy January 27, 2018
The art of Leftying. When one male friend touches another male friend's genitalia in a pleasuring manner....with his left hand. Hence, "Lefty".
Dude, how are you doing that?

Oh, it's no biggie. I Lefty myself at home all the time.

Dude, teach me.
Lefty by Dan Nobile March 7, 2009
Usually spread across social media and typically used as a insult to anyone who may be perceived as holding left-wing views. If the use of the term 'lefty' isn't backed up with any justification in an argument, it's a good indication they cannot form a rebuttal and only want to cease the argument. Further prodding after being called a 'lefty' usually results in being compared to a child, snowflake, stupid, degenerate, or anything which the initial user of the word 'lefty' isn't already.
'There is not yet an iota of proof that Halal funds terrorism.'

'It's that kind of lefty crap that kept ISIS going for so long.'
Lefty by Leftist degenerate August 17, 2018
1. a right handed male who masturbates predominately with his left hand. serves as an annoying to him and funny to everyone else nickname that may earn you slaps on the face if said too often.

2. a character in the book Youth in Revolt, so called because of the above
Taylor: "hey LEFTY"

Ivan: "Damn it, don't call me that! my name is Ivan! *slaps Taylor*"