XO

XO is slang for cannabis considered an exotic strain.

"Last night we were smoking on some XO and it hit me hard"

by Grizz.Ñ July 8, 2022

XO

a really 1980's way of saying cool, see also gnarly don't belive me it was in commercials....

"these cakes are really XO"

by NatE March 4, 2004

XO

Xterminate Opps
Meaning kill your opps

Usually a term used by African American rapper HoodYoungin XO

We don’t go by disrespect we gonna have to XO

by Almighty 666 😈 December 13, 2020

xo's

Another name for the street drug ecstasy. An ecstasy pill.

"Can I get some xo's for 10 a pill?"

"Hell naw."

by I know the lingo November 13, 2007

xo

X= ecstacy o=oxycodone the weeknds logo/crew

We reppin xo till the death

by TillTheDeathXO August 6, 2015

Xo

extacy pills

gone off them xo's in the club.

by darrylepoullard December 11, 2003

Xo

This is the "D'oh Face" emoticon. The capital X representing Homer Simpson's squinting eyes and the small "o" to represent the shape of his mouth as he exclaims, "D'oh!"

Alternately it can appear as: X0 or Xo!

It is meant to be distinct from XO, which represents kiss and hug—so be careful.

I spoke too soon when I declared that I was "King of the World." Xo

by malijn November 11, 2011