Something that rubs you the wrong way, and chafes you. Although your skin is not actually chafed, a person or disruption to a good situation, is a chafe.
A chafe can also be exclaimed as a buzz kill. "Oh, what a chafe! The dvd is scratched and right at my favorite part of the movie!"
An alternate slang word invented by an Usman and a Hussain during the consumption of a WolfBane. The word is now quickly being spread and used by several students studying at London Universities (predominantly City University).
It is an alternate word for safe, best described by Author KitSteel.
variations include chafety, chafety bells, chafety pins.