loco 

plum crazy, out of your mind, wild beyond all control, having eaten of loco weed

you're plum loco to date that chick, man; her dad's the Man

loco by Catherine Dunn August 29, 2008

Loco 

It has two meanings the first one is like crazy , insane and that things and the other meaning is like a really close friend like your brother

Hey loco how are you ?

And in Spanish is used like this :

Oye loco como estas ?

Loco by Saannn December 2, 2015

Loco 

Sometimes used as crazy but can also mean my/your location

What’s your loco?
My loco is . . .

Loco by yeetsurkid September 2, 2019

LoCo 

Short for Loudoun County VA

Where you from? I'm from LoCo bitch!!

LoCo by th3m0nk July 29, 2006

Loco 

What happens when you tell a conservative they are the english version of a republican.

Liberal/Labour member: Harry Smith, did conservatives are basically English republicans.
Conservative Smith: No, no, no, no, no *starts rabidly shaking* I am not. *goes LOCO*
Liberal/labour member: no need to go crazy for coco pops

Loco by Iminclassrightnow October 6, 2018

loco 

when two lines of people are close together and somebody runs through and everyone in the two lines severly punches the runner. practiced in team sports as a form of punishment. extremly painful.

coach: how can you miss thet penalty kick...you have a loco.

player: NOO!! not a loco please have mercy!!

loco by nigger2546 March 18, 2009

Loco 

Loco is a spanish slang word there means crazy/insane.

"So they think i'm loco".

Loco by Mulatto Girl November 8, 2010