Lampoona Share definition Flag It is a vagina that has a yeast infection and has been torn out of the girl. Commonly refered to hookers on the street Joe: Look at the hooker Bob: Yah, her lampoona is in her hand! Lampoona by Dboy69 October 22, 2010 0 0 Get merch Get the Lampoona mug. Buy Now — $32.95 See more merch