1. To be in serious trouble.
2. A word describing something in a state of disrepair.
3. A word to describe a person who is heavily under the influence of alcohol and/or narcotic material, to an extent where it affects their behavioural patterns.
1. "When my parents found out I killed their parrot, I'm screwed!"
2. "Wow, someone screwed that car up pretty bad!"
3. "Wow, that guy is screwed!"