the third mutation of the the pronoun you in the dialect between boston and philly used to emphasize a point
Youse guys have no friggin idea how bad i'm gonna beat your skulls in for this!
by AdamRich January 30, 2007
A version of "you guys," which is mostly associated with New Jersey, but is also heard in other metropolitan areas, such as New York and Chicago.

It may also be spelled "yous guys" and is much better than saying "y'all."
Youse guys want to go to the concert tonight?
by ChemicalGoat May 18, 2009
a whack way of saying y'all
youse guys are lame.
by mr. cool guy August 19, 2006