When you're getting rid of someone or something in your life.
They're so toxic in my life! I'm just going to wash my hands of them and move on.
by DickDFW July 28, 2017
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A more direct way of alerting someone that you are no longer available to whine to.
Mary: Chad cheated on me and I really need someone to talk to.

You: I'm not going to say: "I told you so". I'm washing my hands of this madness.
by Felhamster October 13, 2009
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