1) a state of being that resembles chemical impairment in which life is good because it sucks and pain does not exist.....till the next morning

2) feeling you get after consuming a glorious amount of vodka without a hangover or vomiting

3) drunk
" After her b/f broke up with her, she sang and danced like a whore...clearly in total Vodka Afterglow."

"The guy that just tripped over your car was in total vodka afterglow."
by Ali Butz May 3, 2008