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An insult for a guy who is half-Jewish (generally used if their father is Jewish). Is meant to imply that they are only half-circumcised.

A stereotype of twoskins is they have "Reverse Jew Syndrome", wherein they are susceptible to blatant rip-offs.
You bought a can of soda for five dollars? You're such a twoskin.
by Thomas Hutchinson February 01, 2007
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2
The skill of sticking two small Rizla (cigarette papers) together which are then used to roll a larger Spliff.
Dam I've lost my kings, I'll have to stick a two skin.

Dude don't be stingey, roll a two skin.
by NorfolkWeed July 15, 2008
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3
When Nick whipped out his penis for biology, he said that he had foreskin. However, the teacher corrected him by stating that his foreskin is actually only two skin.
by Alexei The Russian December 15, 2008
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4
It's when you get a half circumcision not a the full. You no longer have a foreskin you have a twoskin. It's either cut vertically or horizontally. A vertical cut is know as window dressing and a horizontal cut is known as a lower bowl, or upper bowl.
My father is Jewish and my mother is not so they decided on a twoskin
by Dr. Twoskin February 03, 2018
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