chronically tense, unable to relax, highly reactive
My cat is so tightly wound he springs up off the floor if anything startles him, and he startles at the drop of a feather.
by Auntie Leah August 5, 2006
Dwight: "She's not the kind of person you would expect to see on Valentine's Day... She is like..."
Pam: "like tightly wound?'
by theofficefan September 12, 2021