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(taxes + toxicosis) - a seasonal depression caused by tax preparations; an acute condition of majority of population every March and April. Symptoms: weakness, exhaustion, nausea, melancholy, etc.

Cf. toxicosis, a pathological condition caused by the action of a poison or toxin.
You look a sort of depressed. What happened? - A usual spring condition: taxicosis.
taxicosis by Mike March 30, 2008
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When it's been too long since you've gorged yourself on tacos. Your blood/hot sauce ratio drops to critical levels and your body reacts by going into Tacosis. Symptoms include irritability, bouncing leg, repetitive side-eye, and an obsession with checking how long until it's Tuesday.
Why is Jan fidgeting with that packet of taco sauce and yelling at everyone?
She's gonna have bitchy Tacosis until she decimates a Fuzzy Bangin' Shrimp Taco Plate...
Tacosis by DeCryptIcon March 9, 2022
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