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A spelling mistake. Like the commonly used work typo(meaning a mistake in typing), a spello refers to a spelling mistake.
Ruby: "I think its spelt as 'disguise'."
Hannah: "Oh, a spello! My bad."
by Manddo September 15, 2005
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Named for Peter Spellos, a prolific B-list actor of unfortunate looks. Used to connote severe unattractiveness, bordering on the grotesque
"He's not just fugly, he's Peter Spellos Fugly."


"Where'd you find Spellos? Shit - you can do better than that!"
by Hartless February 13, 2009
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