To have intercourse with a woman to the point of stupefying ecstasy; to become paralyzed due to a sex partner's exceptional prowess.
"The Golden Girls were fucking hot."
"Yeah, Blanche would run house on me."
by whatwhatinthebutt6969 January 14, 2009
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Another term used for breaking and entering or committing a home invasion.
“Watch out cunt or I’ll run through your fucking house and skin your dog.”

“Do you lads want to get iced up and run through a house tonight?”
by Shelfmaster305 March 30, 2018
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