An extremely vulgar phrase in Italian. Putana means slut/whore/prostitute. The Madonna is Mary, the mother of Jesus. "Madonna" is sometimes translated as "mother of God."

If you say this phrase, you're basically calling Jesus's mom a whore.
Uomo 1: "Mia moglie è incinta da un altro uomo"
Uomo 2: "Putana Madonna! Crepi!"
by diovero August 17, 2007
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1) a plastic bitch.

2) a mannequin-looking bitch that thinks she's all that but really she's just shit from the toilet.
that putana de plastica makes me wish i had a chainsaw! i wanna go texas chainsaw massacre on her ass!!
by betito79 June 2, 2005
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